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Articles imported from Science News Daily: Dog News

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Thanks to avocados' rise to superfood stardom, there are now more avocado-derived products in the supply chain than ever. In a unique study, researchers looked at the possibility of using avocado meal -- the ground, dried, and defatted pulp, seed, and skin left over after avocado oil processing -- as a fiber source in dry dog food.

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German shepherds are predisposed to congenital idiopathic megaesophagus (CIM), an inherited disorder where a puppy develops an enlarged esophagus that fails to move food into their stomachs. Puppies with the condition regurgitate their food and fail to thrive, often leading to euthanasia. Researchers have now developed a genetic test for the disease that German shepherd dog breeders can use to reduce the risk that puppies in future litters will develop the disease.

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COVID in a cat

A study has confirmed what is believed to be the first published account of the delta variant of SARS-CoV-2 in a house cat. The viral sequence was a close match to strains circulating in the Philadelphia area at the same time, underscoring the virus's ability to jump from one species to another without acquiring significant mutations.

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Agility dogs lacking core strength from routine physical exercise may be more susceptible to one of the most common canine knee injuries, a cranial cruciate ligament rupture, which is similar to an ACL tear in humans. According to a research survey documenting activity and injury odds of more than 1,200 agility dogs, just about any physical exercise seems to lower the risk of rupturing the ligament, but some exercises seem to increase the risk. In addition, the size and shape of the dog -- and thereby certain breeds -- were also found to be at higher risk. Balance and core strengthening exercises as well as activities like dock diving, barn hunt and scent work are associated with a decreased rate of ligament rupture.

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Mice are typically used as models in advanced prostate cancer research, but the profound differences between them and humans has long bedeviled the translation of findings from the animal to success in people. Dogs however are the only other animal that suffers from a significant incidence of prostate cancer, and researchers are finding them much more enlightening subjects in identification of drugs that show promise for human patients.

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The Dog Aging Project, founded in 2018, is by far the most ambitious project tackling the question of canine longevity, enrolling and studying tens of thousands of dogs of all sizes, breeds and backgrounds to develop a thorough understanding of canine aging. Their open-source dataset will give veterinarians and scientists the tools to assess how well a specific dog is aging and will set the stage for further research into healthy aging -- in both dogs and people. One of their most intriguing avenues of inquiry will analyze the DNA of exceptionally long-lived dogs, the 'super-centenarians' of the dog world.

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Popular belief has been that small dogs, such as Pomeranians and Chihuahuas, exist because once dogs were domesticated, humans wanted small, cute companions. But researchers now identify a genetic mutation in a growth hormone-regulating gene that corresponds to small body size in dogs that was present in wolves over 50,000 years ago, long before domestication.

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A study of overweight dogs fed a reduced calorie, high-protein, high-fiber diet for 24 weeks found that the dogs' body composition and inflammatory markers changed over time in ways that parallel the positive changes seen in humans on similar diets. The dogs achieved a healthier weight without losing too much muscle mass, and their serum triglycerides, insulin and inflammatory markers all decreased with weight loss.

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A new 'image analysis pipeline' is giving scientists rapid new insight into how disease or injury have changed the body, down to the individual cell. It's called TDAExplore, which takes the detailed imaging provided by microscopy, pairs it with a hot area of mathematics called topology, which provides insight on how things are arranged, and the analytical power of artificial intelligence to give, for example, a new perspective on changes in a cell resulting from ALS and where in the cell they happen, according to a cell biologist involved with the study.

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